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Amuvatinib (MP-470)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606179

A novel RTK inhibitor that effectively inhibits c-Kit, PDGFRalpha and Flt3 with IC50 of 10 nM, 40 nM and 81 nM, respectively. More details

$240 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Amuvatinib, Biochemical
Full Product Name
Amuvatinib
Product Synonym Names
MP-470; MP 470; MP470; HPK-56; HPK56
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
447.5096
Suitability
10mM in DMSO
Target
c-Kit
Receptor
c-Kit (D816H); FLT3 (D835Y); PDGFRalpha (V561D)
Chemical Name
1-Piperazinecarbothioamide, N-(1, 3-benzodioxol-5-ylmethyl)-4-benzofuro[3, 2-d]pyrimidin-4-yl
SMILES
S=C(N1CCN(C2=C(OC3=CC=CC=C34)C4=NC=N2)CC1)NCC5=CC=C(OCO6)C6=C5
Molecular Formula
C23H21N5O3S
CAS Number
850879-09-3

Product Categories/Family for Amuvatinib biochemical

Product References and Citations for Amuvatinib biochemical

1. Mahadevan D, et al. Oncogene. 2007 Jun 7; 26 (27):3909-19.
2. Qi W, et al. BMC Cancer. 2009 May 11; 9:142.
4. Bearss DJ, et al. US Patent, US/2008/0226747.

Other Notes

Small volumes of Amuvatinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Amuvatinib purchase

MBS3606179 is a biochemical targeting Amuvatinib.
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