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MK-0812 succinate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606190

A potent CCR2 specific antagonist that blocks MCP-1 mediated response with an IC50 of 3.2 nM. More details

$300 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-0812 succinate, Biochemical
Full Product Name
MK-0812 succinate
Product Synonym Names
MK 0812 Succinate; MK0812 Succinate
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
587.6283
Suitability
DMSO: >=32mg/mL
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
D-erythro-Pentitol, 1, 5-anhydro-2, 3-dideoxy-3-[[(1R, 3S)-3-[[7, 8-dihydro-3-(trifluoromethyl)-1, 6-naphthyridin-6(5H)-yl]carbonyl]-3-(1-methylethyl)cyclopentyl]amino]-4-O-methyl-, butanedioate(1:1)
SMILES
O=C([C@@]1(C(C)C)C[C@@H](N[C@@H]2[C@H](OC)COCC2)CC1)N3CC4=C(N=CC(C(F)(F)F)=C4)CC3.O=C(O)CCC(O)=O
Molecular Formula
C28H40F3N3O7
CAS Number
851916-42-2

Product Categories/Family for MK-0812 succinate biochemical

Multiple Sclerosis; GPCR/G Protein; Inflammation/Immunology

Structure of MK-0812 succinate biochemical

Mk-0812 Succinate Biochemical – Cat# MBS3606190

Product References and Citations for MK-0812 succinate biochemical

1. Wisniewski T, et al. J Immunol Methods. 2010 Jan 31; 352 (1-2):101-10.
2. O'Brien PD, et al. Diabetes Obes Metab. 2017 Mar 23. doi: 10.1111/dom.12950.
3. Min SH, et al. Biochem Biophys Res Commun. 2010 Jan 1; 391 (1):1080-6.

Other Notes

Small volumes of MK-0812 succinate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0812 succinate purchase

MBS3606190 is a biochemical targeting MK-0812 succinate.
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