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ABT-737

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606192

A BH3 mimetic inhibitor of Bcl-xL, Bcl-2 and Bcl-w with EC50 of 78.7 nM, 30.3 nM and 197.8 nM in cell-free assays, respectively. More details

$250 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ABT-737, Biochemical
Full Product Name
ABT-737
Product Synonym Names
ABT737; ABT 737
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
813.4269
Suitability
10mM in DMSO
Target
Bcl-2
Receptor
Bcl-2; Bcl-B; Bcl-w; Bcl-xL; Bfl-1
Chemical Name
Benzamide, 4-[4-[(4'-chloro[1, 1'-biphenyl]-2-yl)methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(dimethylamino)-1-[(phenylthio)methyl]propyl]amino]-3-nitrophenyl]sulfonyl]
SMILES
O=C(NS(=O)(C1=CC=C(N[C@H](CCN(C)C)CSC2=CC=CC=C2)C([N+]([O-])=O)=C1)=O)C3=CC=C(N4CCN(CC5=CC=CC=C5C6=CC=C(Cl)C=C6)CC4)C=C3
Molecular Formula
C42H45ClN6O5S2
CAS Number
852808-04-9

Product Categories/Family for ABT-737 biochemical

Ovarian Cancer; Angiogenesis; Cancer

Structure of ABT-737 biochemical

ABT-737 Biochemical – Cat# MBS3606192

Product References and Citations for ABT-737 biochemical

1. Oltersdorf T, et al. Nature. 2005 Jun 2; 435 (7042):677-81. 2. Konopleva M, et al. Cancer Cell. 2006 Nov; 10 (5):375-88. 3. Tahir SK, et al. Cancer Res. 2007 Feb 1; 67 (3):1176-83.

Other Notes

Small volumes of ABT-737 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ABT-737 purchase

MBS3606192 is a biochemical targeting ABT-737.
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