WP1130 (Degrasyn)

Name: WP1130 (Degrasyn); MyBioSource
Brand: MyBioSource
SKU: MBS3606204
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606204

WP1130 (Degrasyn) is a small molecule that specifically and rapidly down-regulates both wild-type and mutant Bcr/Abl protein without affecting bcr/abl gene expression (IC50=1.8 uM). More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

WP1130, Biochemical

Full Product Name

WP1130

Product Synonym Names

Degrasyn; WP 1130; WP-1130

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

384.3

Suitability

DMSO: >=33mg/mL

Target

Bcr-Abl

Receptor

Bcr-Abl

Chemical Name

2-Propenamide, 3-(6-bromo-2-pyridinyl)-2-cyano-N-[(1S)-1-phenylbutyl]-, (2E)

SMILES

O=C(N[C@H](C1=CC=CC=C1)CCC)/C(C#N)=C/C2=NC(Br)=CC=C2

Molecular Formula

C19H18BrN3O

CAS Number

856243-80-6

Product Categories/Family for WP1130 biochemical

Angiogenesis; Cancer

Product References and Citations for WP1130 biochemical

1. Bartholomeusz GA, et al. Blood. 2007 Apr 15; 109 (8):3470-8.
2. Bartholomeusz G, et al. Cancer Res. 2007 Apr 15; 67 (8):3912-8.
3. Kapuria V, et al. Cancer Res. 2010 Nov 15; 70 (22):9265-76.
4. Drieen S, et al. Autophagy. 2015; 11 (9):1458-70.

Other Notes

Small volumes of WP1130 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for WP1130 purchase

MBS3606204 is a biochemical targeting WP1130.