• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

LY2228820 dimesylate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606239

LY2228820 dimesylate (Ralimetinib) is a potent, selective, orally available inhibitor p38 MAPK with IC50 of 5.3 and 3.2 nM for p38alpha and p38beta, respectively. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
LY2228820 dimesylate, Biochemical
Full Product Name
LY2228820 dimesylate
Product Synonym Names
Ralimetinib dimesylate; LY2228820; LY-2228820
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
612.737
Suitability
DMSO: <7.8mg/mL
Target
p38 MAPK
Receptor
p38alpha
Chemical Name
3H-Imidazo[4, 5-b]pyridin-2-amine, 5-[2-(1, 1-dimethylethyl)-4-(4-fluorophenyl)-1H-imidazol-5-yl]-3-(2, 2-dimethylpropyl)-, methanesulfonate(1:2)
SMILES
CS(O)(=O)=O.CS(O)(=O)=O.CC(C)(C)CN1C(N)=NC2=C1N=C(C=C2)C1=C(N=C(N1)C(C)(C)C)C1=CC=C(F)C=C1
Molecular Formula
C26H37FN6O6S2
CAS Number
862507-23-1

Product Categories/Family for LY2228820 dimesylate biochemical

Ovarian Cancer; MAPK/ERK Signaling; Cancer

Structure of LY2228820 dimesylate biochemical

LY2228820 dimesylate Biochemical – Cat# MBS3606239

Product References and Citations for LY2228820 dimesylate biochemical

1. Tate CM, et al. J Biol Chem. 2013 Mar 1; 288 (9):6743-53.
2. Campbell RM, et al. Mol Cancer Ther. 2014 Feb; 13 (2):364-74.
3. Ishitsuka K, et al. Br J Haematol. 2008 May; 141 (5):598-606.
4. Patnaik A, et al. Clin Cancer Res. 2016 Mar 1; 22 (5):1095-102.

Other Notes

Small volumes of LY2228820 dimesylate biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2228820 dimesylate purchase

MBS3606239 is a biochemical targeting LY2228820 dimesylate.
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000