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It1t (Isothiourea 1t)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606268

A highly potent, selective, orally bioavailable CXCR4 inhibitor with binding IC50 of 8 nM for hCXCR4, IC50 of 1.1 nM in Ca2+-mobilization assays. More details

$875 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IT1t, Biochemical
Full Product Name
IT1t
Product Synonym Names
Isothiourea 1t
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
406.65146
Suitability
DMSO
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
Carbamimidothioic acid, N, N'-dicyclohexyl-, (5, 6-dihydro-6, 6-dimethylimidazo[2, 1-b]thiazol-3-yl)methyl ester
SMILES
CC1(CN2C(=CSC2=N1)CSC(=NC3CCCCC3)NC4CCCCC4)C
Molecular Formula
C21H34N4S2
CAS Number
864677-55-4

Product Categories/Family for IT1t biochemical

Structure of IT1t biochemical

It1t Isothiourea 1t Biochemical – Cat# MBS3606268

Product References and Citations for IT1t biochemical

1. Wu B, et al. Science. 2010 Nov 19; 330 (6007):1066-71.
2. Thoma G, et al. J Med Chem. 2008 Dec 25; 51 (24):7915-20.
3. Das D, et al. Antimicrob Agents Chemother. 2015 Apr; 59 (4):1895-904.
4. Tulotta C, et al. Dis Model Mech. 2016 Feb; 9 (2):141-53.

Other Notes

Small volumes of IT1t biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IT1t purchase

MBS3606268 is a biochemical targeting IT1t.
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