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Af 353 (Ro-4)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606277

AF-353 is a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist, inhibits human and rat P2X3 (pIC50= 8.0). More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AF 353, Biochemical
Full Product Name
AF 353
Product Synonym Names
Ro-4
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
400.21
Suitability
DMSO: 10mM
Target
P2 Receptor
Receptor
P2X3
Chemical Name
5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2, 4-diamine
SMILES
NC1=NC=C(OC2=CC(I)=C(OC)C=C2C(C)C)C(N)=N1
Molecular Formula
C14H17IN4O2
CAS Number
865305-30-2

Product Categories/Family for AF 353 biochemical

Structure of AF 353 biochemical

Af 353 Ro-4 Biochemical – Cat# MBS3606277

Product References and Citations for AF 353 biochemical

1.Gever JR, et al. Br J Pharmacol. 2010 Jul; 160 (6):1387-1398.

Other Notes

Small volumes of AF 353 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AF 353 purchase

MBS3606277 is a biochemical targeting AF 353.
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