Cx-3543 (Quarfloxin)

Name: Cx-3543 (Quarfloxin); MyBioSource
Brand: MyBioSource
SKU: MBS3606278
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606278

CX-3543 (Quarfloxin, Itarnafloxin) is a small molecule nucleolus-targeting agent that selectively disrupts nucleolin/rDNA G-quadruplex complexes in the nucleolus. More details

$265 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CX-3543, Biochemical

Full Product Name

CX-3543

Product Synonym Names

Quarfloxin; Itarnafloxin

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

604.67

Target

DNA/RNA Synthesis

Receptor

DNA/RNA Synthesis

Chemical Name

5-fluoro-N-(2-((S)-1-methylpyrrolidin-2-yl)ethyl)-3-oxo-6-((R)-3-(pyrazin-2-yl)pyrrolidin-1-yl)-3H-benzo[b]pyrido[3, 2, 1-kl]phenoxazine-2-carboxamide

SMILES

O=C(C1=CN2C3=C(C(N4C[C@H](C5=NC=CN=C5)CC4)=C(F)C=C3C1=O)OC6=CC7=CC=CC=C7C=C26)NCC[C@H]8N(C)CCC8

Molecular Formula

C35H33FN6O3

CAS Number

865311-47-3

Product Categories/Family for CX-3543 biochemical

Blood cancer; Cell Cycle/DNA Damage; Cancer

Product References and Citations for CX-3543 biochemical

1. Drygin D, et al. Cancer Res. 2009 Oct 1; 69 (19):7653-61.
2. Stokes JM, et al. Nat Chem Biol. 2015 Dec; 11 (12):924-32.
3. Xu H, et al. Nat Commun. 2017 Feb 17; 8:14432.

Other Notes

Small volumes of CX-3543 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CX-3543 purchase

MBS3606278 is a biochemical targeting CX-3543.