Mk-8591 (Islatravir)

Name: Mk-8591 (Islatravir); MyBioSource
Brand: MyBioSource
SKU: MBS3606281
Price: 320 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606281

MK-8591 (Islatravir, MK8591, EFdA) is a nucleoside analog that exhibits remarkable potency against wild-type and drug-resistant HIVs. More details

$320 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MK-8591, Biochemical

Full Product Name

MK-8591

Product Synonym Names

Islatravir; MK8591; EFdA

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

293.25

Target

HIV

Receptor

HIV

Chemical Name

(2R, 3S, 5R)-5-(6-amino-2-fluoro-9H-purin-9-yl)-2-ethynyl-2-(hydroxymethyl)tetrahydrofuran-3-ol

SMILES

NC1=C(N=CN2[C@H]3C[C@@H]([C@@](O3)(C#C)CO)O)C2=NC(F)=N1

Molecular Formula

C12H12FN5O3

CAS Number

865363-93-5

Product Categories/Family for MK-8591 biochemical

HIV Infection; Microbiology/Virology; Infection

Product References and Citations for MK-8591 biochemical

1. Wu VH, et al. Antimicrob Agents Chemother. 2017 Jul 25; 61 (8). pii: e00744-17.
2. Salie ZL, et al. Proc Natl Acad Sci U S A. 2016 Aug 16; 113 (33):9274-9.
3. Michailidis E, et al. J Biol Chem. 2014 Aug 29; 289 (35):24533-48.

Other Notes

Small volumes of MK-8591 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-8591 purchase

MBS3606281 is a biochemical targeting MK-8591.