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MLN8054

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606310

A potent, selective, ATP-competitive, orally active Aurora A kinase inhibitor with IC50 of 4 nM. More details

$250 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MLN8054, Biochemical
Full Product Name
MLN8054
Product Synonym Names
MLN-8054; MLN 8054
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
476.862
Suitability
10mM in DMSO
Target
Aurora Kinase
Receptor
AuroraA; AuroraB; CK2; Lck; PKA
Chemical Name
Benzoic acid, 4-[[9-chloro-7-(2, 6-difluorophenyl)-5H-pyrimido[5, 4-d][2]benzazepin-2-yl]amino]
SMILES
O=C(O)C1=CC=C(NC2=NC=C3C(C4=CC=C(Cl)C=C4C(C5=C(F)C=CC=C5F)=NC3)=N2)C=C1
Molecular Formula
C25H15ClF2N4O2
CAS Number
869363-13-3

Product Categories/Family for MLN8054 biochemical

Solid Tumors; Cell Cycle/DNA Damage; Cancer

Structure of MLN8054 biochemical

MLN8054 Biochemical – Cat# MBS3606310

Product References and Citations for MLN8054 biochemical

1. Manfredimg, et al. Proc Natl Acad Sci U S A. 2007 Mar 6; 104 (10):4106-11.
2. Hoar K, et al. Mol Cell Biol. 2007 Jun; 27 (12):4513-25.
3. Dar AA, et al. Cancer Res. 2008 Nov 1; 68 (21):8998-9004.
4. Macarulla T, et al. Mol Cancer Ther. 2010 Oct; 9 (10):2844-52.

Other Notes

Small volumes of MLN8054 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MLN8054 purchase

MBS3606310 is a biochemical targeting MLN8054.
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