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MK-2048

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606314

MK-2048 is a potent inhibitor of HIV-1 integrase (IN) and IN mutant R263K with IC50 of 2.6 nM and 1.5 nM, respectively. More details

$355 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-2048, Biochemical
Full Product Name
MK-2048
Product Synonym Names
MK 2048; MK2048
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
461.8784
Suitability
10mM in DMSO
Target
HIV
Receptor
Integrase; Integrase (R263K)
Chemical Name
Pyrazino[1', 2':1, 5]pyrrolo[2, 3-d]pyridazine-4-carboxamide, 2-[(3-chloro-4-fluorophenyl)methyl]-8-ethyl-1, 2, 6, 7, 8, 9-hexahydro-10-hydroxy-N, 6-dimethyl-1, 9-dioxo-, (6S)
SMILES
O=C(C(C1=C2C(O)=C3N1[C@@H](C)CN(CC)C3=O)=NN(CC4=CC=C(F)C(Cl)=C4)C2=O)NC
Molecular Formula
C21H21ClFN5O4
CAS Number
869901-69-9

Product Categories/Family for MK-2048 biochemical

HIV Infection; Microbiology/Virology; Infection

Structure of MK-2048 biochemical

Mk-2048 Biochemical – Cat# MBS3606314

Product References and Citations for MK-2048 biochemical

1. Quashie PK, et al. J Virol. 2012 Mar; 86 (5):2696-705.
2. Van Wesenbeeck L, et al. Antimicrob Agents Chemother. 2011 Jan; 55 (1):321-5.
3. Bar-Magen T, et al. J Virol. 2010 Sep; 84 (18):9210-6.
4. Marsden MD, et al. Antimicrob Agents Chemother. 2011 Aug; 55 (8):3696-702.

Other Notes

Small volumes of MK-2048 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-2048 purchase

MBS3606314 is a biochemical targeting MK-2048.
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