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MK-0893

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606321

A potent, selective, reversible and competitive antagonist of glucagon receptor with high binding affinity (IC(=50=6.6 nM) and functional cAMP activity (IC50=15.7 nM). More details

$430 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MK-0893, Biochemical
Full Product Name
MK-0893
Product Synonym Names
MK0893; MK 0893
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
588.4805
Suitability
10mM in DMSO
Target
Glucagon Receptor
Receptor
Glucagon Receptor
Chemical Name
.beta.-Alanine, N-[4-[(1S)-1-[3-(3, 5-dichlorophenyl)-5-(6-methoxy-2-naphthalenyl)-1H-pyrazol-1-yl]ethyl]benzoyl]
SMILES
CC(C1=CC=C(C=C1)C(=O)NCCC(=O)O)N2C(=CC(=N2)C3=CC(=CC(=C3)Cl)Cl)C4=CC5=C(C=C4)C=C(C=C5)OC
Molecular Formula
C32H27Cl2N3O4
CAS Number
870823-12-4

Product Categories/Family for MK-0893 biochemical

Diabetes; GPCR/G Protein; Metabolic Disease

Structure of MK-0893 biochemical

Mk-0893 Biochemical – Cat# MBS3606321

Product References and Citations for MK-0893 biochemical

1. Xiong Y, et al. J Med Chem. 2012 Jul 12; 55 (13):6137-48.
2. Guan HP, et al. J Lipid Res. 2015 Nov; 56 (11):2183-95.
3. Jazayeri A, et al. Nature. 2016 May 12; 533 (7602):274-7.

Other Notes

Small volumes of MK-0893 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-0893 purchase

MBS3606321 is a biochemical targeting MK-0893.
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