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Tpl2-IN-2p

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606325

A potent, selective, reversible and ATP-competitive inhibitor of Tpl2 kinase with IC50 of 50 nM. More details

$475 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tpl2-IN-2p, Biochemical
Full Product Name
Tpl2-IN-2p
Product Synonym Names
c-Cot Kinase Inhibitor; MAP3K8 Kinase Inhibitor; Tumor Progression Locus 2 Kinase Inhibitor
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
404.83
Target
MEK
Receptor
MEK
Chemical Name
4-((3-chloro-4-fluorophenyl)amino)-6-((pyridin-3-ylmethyl)amino)-1, 7-naphthyridine-3-carbonitrile
SMILES
N#CC1=C(NC2=CC=C(F)C(Cl)=C2)C3=CC(NCC4=CC=CN=C4)=NC=C3N=C1
Molecular Formula
C21H14ClFN6
CAS Number
871307-18-5

Product Categories/Family for Tpl2-IN-2p biochemical

MAPK/ERK Signaling

Structure of Tpl2-IN-2p biochemical

Tpl2-in-2p Biochemical – Cat# MBS3606325

Product References and Citations for Tpl2-IN-2p biochemical

1. Gavrin LK, et al. Bioorg Med Chem Lett. 2005 Dec 1; 15 (23):5288-92.
2. Lee WJ, et al. Neoplasia. 2013 Sep; 15 (9):1036-48.
3. Lee HW, et al. Mol Cancer Res. 2013 Nov; 11 (11):1375-86.

Other Notes

Small volumes of Tpl2-IN-2p biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tpl2-IN-2p purchase

MBS3606325 is a biochemical targeting Tpl2-IN-2p.
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