As 703569 (R763)

Name: As 703569 (R763); MyBioSource
Brand: MyBioSource
SKU: MBS3606327
Price: 395 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606327

Cenisertib (AS 703569;R763) is a novel potent, orally available inhibitor of Aurora kinases, exhibits signifficant anti-proliferative activity against a wide range of tumor cells both in vitro and in vivo (A549 EC50=9 nM). More details

$395 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AS 703569, Biochemical

Full Product Name

AS 703569

Product Synonym Names

R763; Cenisertib

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

451.54

Target

Aurora Kinase

Receptor

Aurora Kinase

Chemical Name

(1S, 2S, 3R, 4R)-3-((5-fluoro-2-((3-methyl-4-(4-methylpiperazin-1-yl)phenyl)amino)pyrimidin-4-yl)amino)bicyclo[2.2.1]hept-5-ene-2-carboxamide

SMILES

O=C([C@H]1[C@](C2)([H])C=C[C@]2([H])[C@H]1NC3=NC(NC4=CC=C(N5CCN(C)CC5)C(C)=C4)=NC=C3F)N

Molecular Formula

C24H30FN7O

CAS Number

871357-89-0

Product Categories/Family for AS 703569 biochemical

Solid Tumors; Cell Cycle/DNA Damage; Cancer

Product References and Citations for AS 703569 biochemical

1. McLaughlin J, et al. J Cancer Res Clin Oncol. 2010 Jan; 136 (1):99-113.
2. Illert AL, et al. PLoS One. 2014 Nov 26; 9 (11):e112318.
3. Peter B, et al. Leukemia. 2017 Nov 29. doi: 10.1038/leu.2017.338.

Other Notes

Small volumes of AS 703569 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AS 703569 purchase

MBS3606327 is a biochemical targeting AS 703569.