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GDC-0152

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606347

GDC-0152 is a potent antagonist of XIAP-BIR3, ML-IAP-BIR3, cIAP1-BIR3 and cIAP2-BIR3 with Ki of 28 nM, 14 nM, 17 nM and 43 nM, respectively. More details

$255 / 1mL*10mM (in DMSO) +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDC-0152, Biochemical
Full Product Name
GDC-0152
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
498.64
Suitability
DMSO: 99mg/mL (198.54mM)
Ethanol: 99mg/mL (198.54mM)
Water: 3mg/mL (6.01mM)
Target
IAP
Receptor
cIAP1-BIR3; cIAP2-BIR3; MLXBIR3SG; XIAP-BIR2; XIAP-BIR3
SMILES
CN[C@@H](C)C(=O)N[C@@H](C1CCCCC1)C(=O)N1CCC[C@H]1C(=O)NC1=C(N=NS1)C1=CC=CC=C1|r,c:28,34,36,t:26,32|
Molecular Formula
C25H34N6O3S
CAS Number
873652-48-3

Product Categories/Family for GDC-0152 biochemical

Apoptosis; Cancer

Structure of GDC-0152 biochemical

GDC-0152 Biochemical – Cat# MBS3606347

Product References and Citations for GDC-0152 biochemical

1.Flygare JA, et al. J Med Chem, 2012, 55 (9), 4101-4113.

Other Notes

Small volumes of GDC-0152 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0152 purchase

MBS3606347 is a biochemical targeting GDC-0152.
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