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AZD 5069

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606371

AZD 5069 (AZD5069) is a potent, selective, slowly reversible and orally bioavailable CXCR2 antagonist that inhibits CXCL8 binding to CXCR2 with pIC50 of 9.1. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AZD 5069, Biochemical
Full Product Name
AZD 5069
Product Synonym Names
AZD5069; AZD-5069
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
476.51
Suitability
DMSO: 90mg/mL (188.87mM)
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
N-(2-((2, 3-difluorobenzyl)thio)-6-(((2R, 3S)-3, 4-dihydroxybutan-2-yl)oxy)pyrimidin-4-yl)azetidine-1-sulfonamide
SMILES
O=S(N1CCC1)(NC2=NC(SCC3=CC=CC(F)=C3F)=NC(O[C@H](C)[C@@H](O)CO)=C2)=O
Molecular Formula
C18H22F2N4O5S2
CAS Number
878385-84-3

Product Categories/Family for AZD 5069 biochemical

Pancreatic Cancer; GPCR/G Protein; Cancer

Structure of AZD 5069 biochemical

AZD 5069 Biochemical – Cat# MBS3606371

Product References and Citations for AZD 5069 biochemical

1. Nicholls DJ, et al. J Pharmacol Exp Ther. 2015 May; 353 (2):340-50.
2. Jurcevic S, et al. Br J Clin Pharmacol. 2015 Dec; 80 (6):1324-36.
3. Kirsten AM, et al. Pulm Pharmacol Ther. 2015 Apr; 31:36-41.
4. Walters I, et la. Bioorg Med Chem Lett. 2008 Jan 15; 18 (2):798-803.

Other Notes

Small volumes of AZD 5069 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AZD 5069 purchase

MBS3606371 is a biochemical targeting AZD 5069.
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