Bafilomycin A1 (NSC 381866)

Name: Bafilomycin A1 (NSC 381866); MyBioSource
Brand: MyBioSource
SKU: MBS3606417
Price: 710 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606417

Bafilomycin A1 is a macrolide antibiotic isolated from the Streptomyces species and an inhibitor of vacuolar V-ATPase. More details

$710 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Bafilomycin A1, Biochemical

Full Product Name

Bafilomycin A1

Product Synonym Names

NSC 381866

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

622.83

Target

Proton Pump

Chemical Name

(3E, 5E, 7R, 8S, 9S, 11E, 13Z, 15S)-16-((2S, 3R, 4S)-4-((2R, 4R, 5S, 6R)-2, 4-dihydroxy-6-isopropyl-5-methyltetrahydro-2H-pyran-2-yl)-3-hydroxypentan-2-yl)-8-hydroxy-3, 15-dimethoxy-5, 7, 9, 11-tetramethyloxacyclohexadeca-3, 5, 11, 13-tetraen-2-one

SMILES

O[C@H]([C@H](C)/C=C(C)/C=C1OC)[C@@H](C)C/C(C)=C/C=C[C@H](OC)C([C@@H](C)[C@H]([C@@H]([C@@]2(O)C[C@@H](O)[C@H](C)[C@@H]([C@H](C)C)O2)C)O)OC/1=O

Molecular Formula

C??H??O?

CAS Number

88899-55-2

Product Categories/Family for Bafilomycin A1 biochemical

Membrane Transporter/Ion Channel; Metabolic Disease

Product References and Citations for Bafilomycin A1 biochemical

1. Yuan N, et al. Bafilomycin A1 targets both autophagy and apoptosis pathways in pediatric B-cell acute lymphoblastic leukemia. Haematologica. 2015 Mar; 100 (3):345-56.
2. Lu X, et al. Bafilomycin A1 inhibits the growth and metastatic potential of the BEL-7402 liver cancer and HO-8910 ovarian cancer cell lines and induces alterations in their microRna expression. Exp Ther Med. 2015 Nov; 10 (5):1829-1834.

Other Notes

Small volumes of Bafilomycin A1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Bafilomycin A1 purchase

MBS3606417 is a biochemical targeting Bafilomycin A1.