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AT-9283

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606444

A multi-targeted kinase inhibitor with potent activity against Aurora A, Aurora B, JAK2, JAK3, and ABL (T315I) with IC50 of 3, 3, 1.2, 1.1, and 4 nM, respectively. More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
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Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AT-9283, Biochemical
Full Product Name
AT-9283
Product Synonym Names
AT9283; AT 9283
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
381.4316
Suitability
10mM in DMSO
Target
Aurora Kinase
Receptor
Abl1 (T315I); AuroraA; AuroraB; JAK2; JAK3
Chemical Name
Urea, N-cyclopropyl-N'-[3-[6-(4-morpholinylmethyl)-1H-benzimidazol-2-yl]-1H-pyrazol-4-yl]
SMILES
C1CC1NC(=O)NC2=CNN/C2=C3/N=C4C=CC(=CC4=N3)CN5CCOCC5
Molecular Formula
C19H23N7O2
CAS Number
896466-04-9

Structure of AT-9283 biochemical

At-9283 Biochemical – Cat# MBS3606444

Product References and Citations for AT-9283 biochemical

1. Howard S, et al. J Med Chem. 2009 Jan 22; 52 (2):379-88.
2. Dawson MA, et al. Br J Haematol. 2010 Jul; 150 (1):46-57.
3. Tanaka R, et al. Blood. 2010 Sep 23; 116 (12):2089-95.

Other Notes

Small volumes of AT-9283 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AT-9283 purchase

MBS3606444 is a biochemical targeting AT-9283.
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