R788 free base (Fostamatinib)

Name: R788 Free Base (Fostamatinib); MyBioSource
Brand: MyBioSource
SKU: MBS3606474
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606474

Fostamatinib (R788) is a prodrug of the active metabolite R406, which is a potent, ATP-competitive inhibitor of Syk kinase with Ki/IC50 of 30/41 nM. More details

$235 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

R788 free base, Biochemical

Full Product Name

R788 free base

Product Synonym Names

Fostamatinib; R788

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

580.4595

Suitability

10mM in DMSO

Target

Syk

Receptor

A3; Adenosinetransporter; Monoaminetransporter; Syk

Chemical Name

2H-Pyrido[3, 2-b]-1, 4-oxazin-3(4H)-one, 6-[[5-fluoro-2-[(3, 4, 5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2, 2-dimethyl-4-[(phosphonooxy)methyl]

SMILES

COC1=CC(NC2=NC=C(F)C(NC3=NC4=C(OC(C)(C)C(=O)N4COP(O)(O)=O)C=C3)=N2)=CC(OC)=C1OC

Molecular Formula

C23H26FN6O9P

CAS Number

901119-35-5

Product Categories/Family for R788 free base biochemical

Rheumatoid Arthritis; Angiogenesis; Inflammation/Immunology

Product References and Citations for R788 free base biochemical

1. Braselmann S, et al. J Pharmacol Exp Ther. 2006 Dec; 319 (3):998-1008.
2. Chen L, et al. Blood. 2008 Feb 15; 111 (4):2230-7.
3. Suljagic M, et al. Blood. 2010 Dec 2; 116 (23):4894-905.

Other Notes

Small volumes of R788 free base biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for R788 free base purchase

MBS3606474 is a biochemical targeting R788 free base.