Tofogliflozin (CSG452)

Name: Tofogliflozin (CSG452); MyBioSource
Brand: MyBioSource
SKU: MBS3606487
Price: 875 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606487

Tofogliflozin (CSG-452) is a potent, highly selective SGLT2 inhibitor with Ki of 2.9, 14.9, and 6.4 nM against human, rat, and mouse SGLT2, respectively. More details

$875 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Tofogliflozin, Biochemical

Full Product Name

Tofogliflozin

Product Synonym Names

CSG452; CSG-452

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

386.444

Suitability

10mM in DMSO

Target

SGLT

Receptor

SGLT

Chemical Name

Spiro[isobenzofuran-1(3H), 2'-[2H]pyran]-3', 4', 5'-triol, 6-[(4-ethylphenyl)methyl]-3', 4', 5', 6'-tetrahydro-6'-(hydroxymethyl)-, (1S, 3'R, 4'S, 5'S, 6'R)

SMILES

CCC1=CC=C(C=C1)CC2=CC3=C(COC34C(C(C(C(O4)CO)O)O)O)C=C2

Molecular Formula

C22H26O6

CAS Number

903565-83-3

Product Categories/Family for Tofogliflozin biochemical

Diabetes; GPCR/G Protein; Metabolic Disease

Product References and Citations for Tofogliflozin biochemical

1. Suzuki M, et al. J Pharmacol Exp Ther. 2012 Jun; 341 (3):692-701.
2. Ohtake Y, et al. J Med Chem. 2012 Sep 13; 55 (17):7828-40.
3. Nagata T, et al. Am J Physiol Endocrinol Metab. 2013 Feb 15; 304 (4):E414-23.
4. Nagata T, et al. Br J Pharmacol. 2013 Oct; 170 (3):519-31.

Other Notes

Small volumes of Tofogliflozin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tofogliflozin purchase

MBS3606487 is a biochemical targeting Tofogliflozin.