Mk-8141 (ACT-077825)

Name: Mk-8141 (ACT-077825); MyBioSource
Brand: MyBioSource
SKU: MBS3606490
Price: 1100 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606490

MK-8141 (ACT-077825) is a novel potent, selective, direct Renin inhibitor for the treatment of cardiovascular disorders. More details

$1100 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

MK-8141, Biochemical

Full Product Name

MK-8141

Product Synonym Names

ACT-077825

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

620.615

Target

Renin

Receptor

Renin

Chemical Name

(1S, 5R)-N-cyclopropyl-7-(4-(2-(2, 6-dichloro-4-methylphenoxy)ethoxy)phenyl)-N-(2, 3-dimethylbenzyl)-3, 9-diazabicyclo[3.3.1]non-6-ene-6-carboxamide

SMILES

CC1=C(C(=CC=C1)CN2CC3CC(=C(C(C2)N3C4CC4)C(=O)N)C5=CC=C(C=C5)OCCOC6=C(C=C(C=C6Cl)C)Cl)C

Molecular Formula

C35H39Cl2N3O3

CAS Number

903579-36-2

Product Categories/Family for MK-8141 biochemical

Hypertension; Metabolic Enzyme/Protease; Cardiovascular Disease

Product References and Citations for MK-8141 biochemical

1. Dingemanse J, et al. Pharmacology. 2014; 94 (3-4):135-42. doi: 10.1159/000362822.
2. Nicolas LB, et al. J Cardiovasc Pharmacol. 2013 Jan; 61 (1):42-50.
3. Jones-Burton C, et al. J Am Soc Hypertens. 2010 Sep-Oct; 4 (5):219-26.

Other Notes

Small volumes of MK-8141 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MK-8141 purchase

MBS3606490 is a biochemical targeting MK-8141.