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GDC-0879

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606501

A potent and selective B-Raf kinase inhibitor with IC50 of 0.13 nM against purified B-Raf V600E and a cellular pERK IC50 of 63 nM in the MALME-3M cell line. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GDC-0879, Biochemical
Full Product Name
GDC-0879
Product Synonym Names
GDC0879; GDC 0879
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
334.3718
Suitability
10mM in DMSO
Target
Raf
Receptor
B-Raf
Chemical Name
1H-Inden-1-one, 2, 3-dihydro-5-[1-(2-hydroxyethyl)-3-(4-pyridinyl)-1H-pyrazol-4-yl]-, oxime
SMILES
OCCN1N=C(C2=CC=NC=C2)C(C3=CC4=C(/C(CC4)=N/O)C=C3)=C1
Molecular Formula
C19H18N4O2
CAS Number
905281-76-7

Product Categories/Family for GDC-0879 biochemical

Skin Cancer; MAPK/ERK Signaling; Cancer

Structure of GDC-0879 biochemical

GDC-0879 Biochemical – Cat# MBS3606501

Product References and Citations for GDC-0879 biochemical

1. Wong H, et al. J Pharmacol Exp Ther. 2009 Apr; 329 (1):360-7.
2. Hoeflich KP, et al. Cancer Res. 2009 Apr 1; 69 (7):3042-51.
3. Hansen JD, et al. Bioorg Med Chem Lett. 2008 Aug 15; 18 (16):4692-5.

Other Notes

Small volumes of GDC-0879 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0879 purchase

MBS3606501 is a biochemical targeting GDC-0879.
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