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MI 219

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606518

MI 219 is a potent, specific MDM2-p53 inhibitor with Ki of 5 nM, >10,000-fold selective for MDM2 over MDMX. More details

$1175 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
MI 219, Biochemical
Full Product Name
MI 219
Product Synonym Names
MI219
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
552.468
Target
MDM2-p53
Receptor
MDM2-p53
Chemical Name
(2'R, 3S, 4'R, 5'R)-6-Chloro-4'-(3-chlorophenyl)-N-[(3S)-3, 4-dihydroxybutyl]-2'-(2, 2-dimethylpropyl)-5-fluoro-1, 2-dihydro-2-oxospiro[3H-indole-3, 3'-pyrrolidine]-5'-carboxamide
SMILES
O=C([C@H](N[C@@H]1CC(C)(C)C)[C@H](C2=CC=CC(Cl)=C2)[C@]31C(NC4=C3C=C(F)C(Cl)=C4)=O)NCC[C@H](O)CO
Molecular Formula
C27H32Cl2FN3O4
CAS Number
908027-55-4

Product Categories/Family for MI 219 biochemical

Structure of MI 219 biochemical

Mi 219 Biochemical – Cat# MBS3606518

Product References and Citations for MI 219 biochemical

1. Shangary S, et al. Proc Natl Acad Sci U S A. 2008 Mar 11; 105 (10):3933-8.
2. Peterson LF, et al. Leukemia. 2011 May; 25 (5):761-9.
3. Feng FY, et al. Neoplasia. 2016 Apr; 18 (4):213-22.

Other Notes

Small volumes of MI 219 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for MI 219 purchase

MBS3606518 is a biochemical targeting MI 219.

Additional Details

NCBI/Uniprot data below describe general gene information for MI 219. It may not necessarily be applicable to this product.

Protein Family

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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