Epertinib (S-222611)

Name: Epertinib (S-222611); MyBioSource
Brand: MyBioSource
SKU: MBS3606522
Price: 505 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606522

Epertinib (S-222611) is a novel potent, orally active, reversible EGFR and HER2 inhibitor with IC50 of 1.48, 7.15 and 2.49 nM for EGFR, HER2 and HER4, respectively. More details

$505 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Epertinib, Biochemical

Full Product Name

Epertinib

Product Synonym Names

S-222611; S222611

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

560.026

Target

EGFR

Receptor

EGFR

Chemical Name

(R, Z)-1-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)but-2-yn-1-one O-morpholin-3-ylmethyl oxime

SMILES

CC#C/C(C1=CC2=C(NC3=CC=C(OCC4=CC=CC(F)=C4)C(Cl)=C3)N=CN=C2C=C1)=NOC[C@@H]5NCCOC5

Molecular Formula

C30H27ClFN5O3

CAS Number

908305-13-5

Product Categories/Family for Epertinib biochemical

Breast Cancer; Angiogenesis; Cancer

Product References and Citations for Epertinib biochemical

1. Tanaka H, et al. Cancer Sci. 2014 Aug; 105 (8):1040-8.
2. Spicer J, et al. Eur J Cancer. 2015 Jan; 51 (2):137-45.
3. Tanaka Y, et al. Sci Rep. 2018 Jan 10; 8 (1):343.

Other Notes

Small volumes of Epertinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Epertinib purchase

MBS3606522 is a biochemical targeting Epertinib.