LY2603618 (IC-83)

Name: Ly2603618 (IC-83); MyBioSource
Brand: MyBioSource
SKU: MBS3606534
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606534

A potent and selective small molecule inhibitor of Chk1 (IC50=?7 nM); promotes impaired DNA synthesis and elevates H2A.X phosphorylation indicative of DNA damage and premature entry into mitosis. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

LY2603618, Biochemical

Full Product Name

LY2603618

Product Synonym Names

IC-83; LY 2603618; LY-2603618; Rabusertib

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

436.303

Suitability

DMSO: 29.5mg/mL

Target

Chk

Receptor

Chk1; PDK1

Chemical Name

Urea, N-[5-bromo-4-methyl-2-[(2S)-2-morpholinylmethoxy]phenyl]-N'-(5-methyl-2-pyrazinyl)

SMILES

CC1=CC(=C(C=C1Br)NC(=O)NC2=NC=C(N=C2)C)OC[C@@H]3CNCCO3

Molecular Formula

C18H22BrN5O3

CAS Number

911222-45-2

Product Categories/Family for LY2603618 biochemical

Pancreatic Cancer; Angiogenesis; Cancer

Product References and Citations for LY2603618 biochemical

1. King C, et al. Invest New Drugs. 2014 Apr; 32 (2):213-26.
2. Emiliano Calvo1, et al. Mol Cancer Ther, 2011, A94.

Other Notes

Small volumes of LY2603618 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for LY2603618 purchase

MBS3606534 is a biochemical targeting LY2603618.