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KU-60019

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606627

KU-60019 is an improved analogue of KU-55933, and is a potent, specific inhibitor of ATM kinase with IC50 of 6.3 nM, 270- and 1,600-fold selectivity over DNA-PKcs and ATR. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KU-60019, Biochemical
Full Product Name
KU-60019
Product Synonym Names
KU60019; KU 60019
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
547.6651
Suitability
DMSO: >=30mg/mL
Target
ATM/ATR
Receptor
ATM/ATR
Chemical Name
4-Morpholineacetamide, 2, 6-dimethyl-N-[5-[6-(4-morpholinyl)-4-oxo-4H-pyran-2-yl]-9H-thioxanthen-2-yl]-, (2R, 6S)-rel
SMILES
CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C3)C=CC=C4C5=CC(=O)C=C(O5)N6CCOCC6
Molecular Formula
C30H33N3O5S
CAS Number
925701-46-8

Product Categories/Family for KU-60019 biochemical

Structure of KU-60019 biochemical

Ku-60019 Biochemical – Cat# MBS3606627

Product References and Citations for KU-60019 biochemical

1. Golding SE, et al. Mol Cancer Ther. 2009 Oct; 8 (10):2894-902.
2. Gamper AM, et al. J Biol Chem. 2012 Apr 6; 287 (15):12445-54.
3. Biddlestone-Thorpe L, et al. Clin Cancer Res. 2013 Jun 15; 19 (12):3189-200.
4. Golding SE, et al. Cell Cycle. 2012 Mar 15; 11 (6):1167-73.

Other Notes

Small volumes of KU-60019 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for KU-60019 purchase

MBS3606627 is a biochemical targeting KU-60019.
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