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ENMD-2076

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606673

A multitargeted kinase inhibitor with IC50s of 3/14/23/40 nM for Flt3/Aurora A/Src/VEGFR2; also inhibits Aurora B, c-Kit, FGFR1 (IC50=100-350 nM). More details

$250 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ENMD-2076, Biochemical
Full Product Name
ENMD-2076
Product Synonym Names
ENMD 2076; ENMD2076
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
375.4701
Suitability
10mM in DMSO
Target
Aurora Kinase
Receptor
AuroraA; FLT3; RET; Src; VEGFR3/FLT4
Chemical Name
4-Pyrimidinamine, 6-(4-methyl-1-piperazinyl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(1E)-2-phenylethenyl]
SMILES
CC1=CC(=NN1)NC2=CC(=NC(=N2)C=CC3=CC=CC=C3)N4CCN(CC4)C
Molecular Formula
C21H25N7
CAS Number
934353-76-1

Product Categories/Family for ENMD-2076 biochemical

Cell Cycle/DNA Damage; Cancer

Structure of ENMD-2076 biochemical

ENMD-2076 Biochemical – Cat# MBS3606673

Product References and Citations for ENMD-2076 biochemical

1. Tentler JJ, et al. Clin Cancer Res. 2010 Jun 1; 16 (11):2989-98.
2. Matulonis UA, et al. Eur J Cancer. 2013 Jan; 49 (1):121-31.
3. Fletcher GC, et al. Mol Cancer Ther. 2011 Jan; 10 (1):126-37.

Other Notes

Small volumes of ENMD-2076 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ENMD-2076 purchase

MBS3606673 is a biochemical targeting ENMD-2076.
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