Tg-101209 (SAR-317461)

Name: Tg-101209 (SAR-317461); MyBioSource
Brand: MyBioSource
SKU: MBS3606692
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606692

A potent, selective, orally bioavailable JAK2 inhibitor with IC50 of 6 nM; also inhibits FLT3 (IC50=25 nM) and RET (IC50=17 nM) kinases, weakly inhibits JAK3 (IC50=168 nM). More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TG-101209, Biochemical

Full Product Name

TG-101209

Product Synonym Names

SAR-317461

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

509.6668

Suitability

10mM in DMSO

Target

JAK

Receptor

FLT3; JAK2; JAK3; RET

Chemical Name

Benzenesulfonamide, N-(1, 1-dimethylethyl)-3-[[5-methyl-2-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-4-pyrimidinyl]amino]

SMILES

O=S(C1=CC=CC(NC2=NC(NC3=CC=C(N4CCN(C)CC4)C=C3)=NC=C2C)=C1)(NC(C)(C)C)=O

Molecular Formula

C26H35N7O2S

CAS Number

936091-14-4

Product Categories/Family for TG-101209 biochemical

Bone Cancer; Angiogenesis; Cancer

Product References and Citations for TG-101209 biochemical

1. Pardanani A, et al. Leukemia. 2007 Aug; 21 (8):1658-68.
2. Libani IV, et al. Blood. 2008 Aug 1; 112 (3):875-85.
3. Ciceri P, et al. Nat Chem Biol. 2014 Apr; 10 (4):305-12.
4. Wang Y, et al. Blood. 2009 Dec 3; 114 (24):5024-33.

Other Notes

Small volumes of TG-101209 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TG-101209 purchase

MBS3606692 is a biochemical targeting TG-101209.