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SB-743921

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606725

SB-743921 is a potent, selective kinesin spindle protein (KSP) inhibitor with Ki of 0.1 nM. More details

$275 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SB-743921, Biochemical
Full Product Name
SB-743921
Product Synonym Names
SB743921; SB 743921
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
553.5193
Suitability
10mM in DMSO
Target
Kinesin
Receptor
KSP; KSP (Colo205cells); KSP (MV522cells); KSP (MX1cells); KSP (SKOV3cells)
Chemical Name
Benzamide, N-(3-aminopropyl)-N-[(1R)-1-[7-chloro-4-oxo-3-(phenylmethyl)-4H-1-benzopyran-2-yl]-2-methylpropyl]-4-methyl-, hydrochloride(1:1)
SMILES
CC1=CC=C(C=C1)C(=O)N(CCCN)C(C2=C(C(=O)C3=C(O2)C=C(C=C3)Cl)CC4=CC=CC=C4)C(C)C.Cl
Molecular Formula
C31H34Cl2N2O3
CAS Number
940929-33-9

Product Categories/Family for SB-743921 biochemical

Blood cancer; Cytoskeleton/Cell Adhesion Molecules; Cancer

Structure of SB-743921 biochemical

Sb-743921 Biochemical – Cat# MBS3606725

Product References and Citations for SB-743921 biochemical

1. Good JA, et al. J Med Chem. 2013 Mar 14; 56 (5):1878-93.
2. Holen KD, et al. Cancer Chemother Pharmacol. 2011 Feb; 67 (2):447-54.
3. Zhu L, et al. Anticancer Drugs. 2016 Oct; 27 (9):863-72.
4. Talapatra SK, et al. J Med Chem. 2013 Aug 22; 56 (16):6317-29.

Other Notes

Small volumes of SB-743921 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SB-743921 purchase

MBS3606725 is a biochemical targeting SB-743921.
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