Danirixin (GSK-1325756)

Name: Danirixin (GSK-1325756); MyBioSource
Brand: MyBioSource
SKU: MBS3606810
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606810

Danirixin (GSK-1325756) is a high-affinity, selective and reversible CXCR2 antagonist (IC50=12.5 nM, CXCL8). More details

$275 / 1mL*10mM (in DMSO) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Danirixin, Biochemical

Full Product Name

Danirixin

Product Synonym Names

GSK-1325756

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

441.9041

Suitability

DMSO: 8mg/mL

Target

Chemokine Receptor

Receptor

CXCL8-CXCR2

Chemical Name

Urea, N-[4-chloro-2-hydroxy-3-[(3S)-3-piperidinylsulfonyl]phenyl]-N'-(3-fluoro-2-methylphenyl)

SMILES

ClC(C(S([C@H]1CCCNC1)(=O)=O)=C2O)=CC=C2NC(NC3=CC=CC(F)=C3C)=O

Molecular Formula

C19H21ClFN3O4S

CAS Number

954126-98-8

Product Categories/Family for Danirixin biochemical

COPD; GPCR/G Protein; Inflammation/Immunology

Product References and Citations for Danirixin biochemical

1. Bloomer JC, et al. Eur J Pharm Biopharm. 2017 Apr 3. pii: S0939-6411 (16)31009-8.
2. Miller BE, et al. BMC Pharmacol Toxicol. 2015 Jun 20; 16:18.
3. Busch-Petersen J, et al. J Pharmacol Exp Ther. 2017 Aug; 362 (2):338-346.

Other Notes

Small volumes of Danirixin biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Danirixin purchase

MBS3606810 is a biochemical targeting Danirixin.