Adavosertib (AZD-1775)

Name: Adavosertib (AZD-1775); MyBioSource
Brand: MyBioSource
SKU: MBS3606814
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606814

A potent and selective small-molecule inhibitor of Wee1 kinase with IC50 of 5.2 nM. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Adavosertib, Biochemical

Full Product Name

Adavosertib

Product Synonym Names

AZD-1775; MK-1775

Purity/Purification

98%

Preparation and Storage

Store at -20°C for 1 year.

Molecular Weight

500.60

Suitability

10mM in DMSO

Target

Wee1

Receptor

Wee1

Pathway

Cell Cycle/DNA Damage

Chemical Name

3H-Pyrazolo[3, 4-d]pyrimidin-3-one, 1, 2-dihydro-1-[6-(1-hydroxy-1-methylethyl)-2-pyridinyl]-6-[[4-(4-methyl-1-piperazinyl)phenyl]amino]-2-(2-propen-1-yl)

SMILES

O=C1N(CC=C)N(C2=NC(C(C)(O)C)=CC=C2)C3=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=NC=C31

Molecular Formula

C27H32N8O2

CAS Number

955365-80-7

Product Categories/Family for Adavosertib biochemical

Lung Cancer; Cell Cycle/DNA Damage; Cancer

Product References and Citations for Adavosertib biochemical

1. Hirai H, et al. Mol Cancer Ther. 2009 Nov; 8 (11):2992-3000.
2. Hirai H, et al. Cancer Biol Ther. 2010 Apr 1; 9 (7):514-22.
3. Bridges KA, et al. Clin Cancer Res. 2011 Sep 1; 17 (17):5638-48.

Other Notes

Small volumes of Adavosertib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Adavosertib purchase

MBS3606814 is a biochemical targeting Adavosertib.