GDC-0941 (Pictilisib)

Name: GDC-0941 (Pictilisib); MyBioSource
Brand: MyBioSource
SKU: MBS3606828
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606828

A potent, selective, orally bioavailable inhibitor of class I PI3Ks with IC50 of 3/33/3/75 nM for p110alpha/beta/gamma/delta, respectively. More details

$220 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GDC-0941, Biochemical

Full Product Name

GDC-0941

Product Synonym Names

Pictilisib

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

513.6356

Suitability

DMSO: >=29mg/mL

Target

PI3K

Receptor

mTOR; p110alpha; p110beta; p110gamma; p110delta

Chemical Name

Thieno[3, 2-d]pyrimidine, 2-(1H-indazol-4-yl)-6-[[4-(methylsulfonyl)-1-piperazinyl]methyl]-4-(4-morpholinyl)

SMILES

CS(=O)(=O)N1CCN(CC2=CC3=C(S2)C(=NC(=N3)C2=C3C=NNC3=CC=C2)N2CCOCC2)CC1

Molecular Formula

C23H27N7O3S2

CAS Number

957054-30-7

Product Categories/Family for GDC-0941 biochemical

Breast Cancer; PI3K/Akt/mTOR signaling; Cancer

Product References and Citations for GDC-0941 biochemical

1. Folkes AJ, et al. J Med Chem. 2008 Sep 25; 51 (18):5522-32.
2. Junttila TT, et al. Cancer Cell. 2009 May 5; 15 (5):429-40.
3. Raynaud FI, et al. Mol Cancer Ther. 2009 Jul; 8 (7):1725-38.

Other Notes

Small volumes of GDC-0941 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0941 purchase

MBS3606828 is a biochemical targeting GDC-0941.