ONX-0914 (PR-957)

Name: ONX-0914 (PR-957); MyBioSource
Brand: MyBioSource
SKU: MBS3606851
Price: 290 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606851

ONX-0914 (PR-957) is a potent, selective inhibitor of the chymotrypsin-like subunit of immunoproteasome LMP7 with IC80 More details

$290 / 5 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ONX-0914, Biochemical

Full Product Name

ONX-0914

Product Synonym Names

PR-957; ONX 0914; ONX0914; PR957; PR 957

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

580.6719

Suitability

DMSO: >=35mg/mL

Target

Proteasome

Receptor

LMP7

Chemical Name

L-Tyrosinamide, N-[2-(4-morpholinyl)acetyl]-L-alanyl-O-methyl-N-[(1S)-2-[(2R)-2-methyl-2-oxiranyl]-2-oxo-1-(phenylmethyl)ethyl]

SMILES

O=C(N[C@@H](CC1=CC=CC=C1)C([C@]2(C)OC2)=O)[C@@H](NC([C@@H](NC(CN3CCOCC3)=O)C)=O)CC4=CC=C(OC)C=C4

Molecular Formula

C31H40N4O7

CAS Number

960374-59-8

Product Categories/Family for ONX-0914 biochemical

Proteasome/Ubiquitin; Inflammation/Immunology

Product References and Citations for ONX-0914 biochemical

1. Muchamuel T, et al. Nat Med. 2009 Jul; 15 (7):781-7.
2. Basler M, et al. J Immunol. 2010 Jul 1; 185 (1):634-41.
3. Ichikawa HT, et al. Arthritis Rheum. 2012 Feb; 64 (2):493-503.
4. Verbrugge SE, et al. J Pharmacol Exp Ther. 2012 Apr; 341 (1):174-82.

Other Notes

Small volumes of ONX-0914 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ONX-0914 purchase

MBS3606851 is a biochemical targeting ONX-0914.