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CSN5i-3

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3606995

CSN5i-3 (CSN5 inhibitor 3) is a potent, selective and orally available inhibitor of CSN5 with IC50 of 5.8 nM, the proteolytic subunit of COP9 signalosome (CSN). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CSN5i-3, Biochemical
Full Product Name
CSN5i-3
Product Synonym Names
CSN5 inhibitor 3
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
505.57
Target
Proteasome
Receptor
Proteasome
Chemical Name
3-(difluoromethyl)-N-(6-((5S, 6S)-6-hydroxy-6, 7, 8, 9-tetrahydro-5H-imidazo[1, 5-a]azepin-5-yl)-[1, 1'-biphenyl]-3-yl)-1-isopropyl-1H-pyrazole-5-carboxamide
Molecular Formula
C28H29F2N5O2

Product Categories/Family for CSN5i-3 biochemical

Proteasome/Ubiquitin

Structure of CSN5i-3 biochemical

Csn5i-3 Biochemical – Cat# MBS3606995

Product References and Citations for CSN5i-3 biochemical

1. Schlierf A, et al. Nat Commun. 2016 Oct 24; 7:13166.

Other Notes

Small volumes of CSN5i-3 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CSN5i-3 purchase

MBS3606995 is a biochemical targeting CSN5i-3.
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