GDC-0349

Name: GDC-0349; MyBioSource
Brand: MyBioSource
SKU: MBS3607187
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607187

GDC-0349 is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kalpha and other 266 kinases. Phase 1. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

GDC-0349, Biochemical

Full Product Name

GDC-0349

Product Synonym Names

GDC0349; GDC 0349; GDC-0349; RG7603

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

452.55

Suitability

DMSO: >=100mg/mL (220.97mM)

Target

Raf

Receptor

mTOR; PI3Kalpha

Chemical Name

(S)-1-ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5, 6, 7, 8-tetrahydropyrido[3, 4-d]pyrimidin-2-yl)phenyl)urea

SMILES

CCNC(=O)NC1=CC=C(C=C1)C1=NC(N2CCOC[C@@H]2C)=C2CCN(CC2=N1)C1COC1

Molecular Formula

C24H32N6O3

CAS Number

1207360-89-1

Product Categories/Family for GDC-0349 biochemical

MAPK/ERK Signaling; Cancer

Product References and Citations for GDC-0349 biochemical

1. Zhonghua Pei, et al. J Med Chem, 2013, 56 (7), 3090-3101.

Other Notes

Small volumes of GDC-0349 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GDC-0349 purchase

MBS3607187 is a biochemical targeting GDC-0349.

GDC-0349

Product Overview

Product Categories/Family for GDC-0349 biochemical

Structure of GDC-0349 biochemical

Related Product Information for GDC-0349 biochemical

Product References and Citations for GDC-0349 biochemical

Other Notes

Searchable Terms for GDC-0349 purchase