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CNX-2006

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607259

CNX-2006 is a novel irreversible mutant-selective EGFR inhibitor with IC50 of < 20 nM, with very weak inhibition at wild-type EGFR. More details

$250 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CNX-2006, Biochemical
Full Product Name
CNX-2006
Product Synonym Names
CNX2006; CNX 2006; CNX-2006.
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
545.53
Suitability
DMSO: >=52mg/mL (95.32mM)
Target
mTOR
Receptor
EGFR (mutant)
Chemical Name
N-(3-((2-((4-((1-(2-fluoroethyl)azetidin-3-yl)amino)-2-methoxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)phenyl)acrylamide
SMILES
COc1c(Nc2ncc(c(Nc3cccc(NC(=O)C=C)c3)n2)C(F)(F)F)ccc(NC2CN(CCF)C2)c1
Molecular Formula
C26H27F4N7O2
CAS Number
1375465-09-0

Product Categories/Family for CNX-2006 biochemical

PI3K/Akt/mTOR signaling; Cancer

Structure of CNX-2006 biochemical

CNX-2006 Biochemical – Cat# MBS3607259

Product References and Citations for CNX-2006 biochemical

1. Ohashi K, et al. 2013

Other Notes

Small volumes of CNX-2006 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CNX-2006 purchase

MBS3607259 is a biochemical targeting CNX-2006.
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