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Cambinol

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607300

Cambinol is a cell-permeable b-naphthol compound that inhibits the NAD-dependent deacetylase activity of SIRT1/2 (IC50: 56/59 uM, respectively) in a substrate-, but not NAD-, competitive manner. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cambinol, Biochemical
Full Product Name
Cambinol
Product Synonym Names
SIRT 1/2 inhibitor IV; NSC112546; NSC-112546
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
360.09
Suitability
DMSO: 50mg/mL (138.72mM)
H2O: <0.1mg/mL
Target
P450
Receptor
SIRT1; SIRT2
Chemical Name
5-((2-hydroxynaphthalen-1-yl)methyl)-6-phenyl-2-thioxo-2, 3-dihydropyrimidin-4(1H)-one
SMILES
O=c1c(Cc2c3ccccc3ccc2O)c(c2ccccc2)[nH]c(=S)[nH]1
Molecular Formula
C21H16N2O2S
CAS Number
14513-15-6

Product Categories/Family for Cambinol biochemical

Metabolic Enzyme/Protease

Structure of Cambinol biochemical

Cambinol Biochemical – Cat# MBS3607300

Product References and Citations for Cambinol biochemical

1. Lugrin J., et al. The sirtuin inhibitor cambinol impairs MAPK signaling, inhibits inflammatory and innate immune responses and protects from septic shock. Biochim Biophys Acta. 2013 Jun; 1833 (6):1498-510.

Other Notes

Small volumes of Cambinol biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cambinol purchase

MBS3607300 is a biochemical targeting Cambinol.
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