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EAI045

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607401

EAI045, an allosteric inhibitor, targets towards drug-resistant EGFR mutants but avoids the wild-type receptor. More details

$220 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EAI045, Biochemical
Full Product Name
EAI045
Product Synonym Names
EAI045; EAI-045; EAI 045
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
383.4
Suitability
DMSO: >=28mg/mL (73.03mM)
Target
p38 MAPK
Receptor
EGFR mutants
Chemical Name
2-(5-fluoro-2-hydroxyphenyl)-2-(3-oxo-1H-isoindol-2-yl)-N-(1, 3-thiazol-2-yl)acetamide
SMILES
c1ccc2c(c1)CN(C2=O)C(C(=O)Nc1sccn1)c1cc(ccc1O)F
Molecular Formula
C19H14FN3O3S
CAS Number
1942114-09-1

Product Categories/Family for EAI045 biochemical

MAPK/ERK Signaling; Cancer

Structure of EAI045 biochemical

EAI045 Biochemical – Cat# MBS3607401

Product References and Citations for EAI045 biochemical

1.Jia Y et al. Overcoming EGFR (T790M) and EGFR (C797S) resistance with mutant-selective allosteric inhibitors. Nature. 2016 May 25; 534 (7605):129-32.

Other Notes

Small volumes of EAI045 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EAI045 purchase

MBS3607401 is a biochemical targeting EAI045.
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