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AST 487 (NVPAST487)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607550

AST 487 is a RET kinase inhibitor, inhibiting RET autophosphorylation and activation of downstream effectors. It also can inhibit Flt-3. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
AST 487, Biochemical
Full Product Name
AST 487
Product Synonym Names
NVPAST487; AST 487
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
529.56
Suitability
DMSO: >=100mg/mL (188.84mM)
Target
HIV
Receptor
c-Kit; RET; FLT4; KDR
Chemical Name
1-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)-3-(4-((6-(methylamino)pyrimidin-4-yl)oxy)phenyl)urea
SMILES
CNc1cc(Oc2ccc(NC(=O)Nc3ccc(CN4CCN(CC)CC4)c(C(F)(F)F)c3)cc2)ncn1
Molecular Formula
C26H30F3N7O2
CAS Number
630124-46-8

Product Categories/Family for AST 487 biochemical

Structure of AST 487 biochemical

AST 487 NVPAST487 Biochemical – Cat# MBS3607550

Product References and Citations for AST 487 biochemical

1. Akeno-Stuart N, et al. Cancer Res. 2007 Jul 15; 67 (14):6956-64.

Other Notes

Small volumes of AST 487 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AST 487 purchase

MBS3607550 is a biochemical targeting AST 487.
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