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VCMMAE

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607555

MBS3607555 is a biochemical targeting VCMMAE. VcMMAE is a drug-linker conjugate for ADC with potent antitumor activity. More details

$215 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VCMMAE, Biochemical
Full Product Name
VCMMAE
Product Synonym Names
VcMMAE; Vc-MMAE; MMAE Vc linker
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
1316.65
Suitability
DMSO: >=54mg/mL (41.01mM)
Target
Potassium Channel
Receptor
Microtubule/Tubulin
Chemical Name
4-((S)-2-((S)-2-(6-(2, 5-dioxo-2, 5-dihydro-1H-pyrrol-1-yl)hexanamido)-3-methylbutanamido)-5-ureidopentanamido)benzyl((S)-1-(((S)-1-(((3R, 4S, 5S)-1-((S)-2-((1R, 2R)-3-(((1S, 2R)-1-hydroxy-1-phenylpropan-2-yl)amino)-1-methoxy-2-methyl-3-oxopropyl)pyrrolidin-1-yl)-3-methoxy-5-methyl-1-oxoheptan-4-yl)(methyl)amino)-3-methyl-1-oxobutan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)(methyl)carbamate
SMILES
CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@H](C)[C@@H](O)c1ccccc1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)OCc1ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN2C(=O)C=CC2=O)C(C)C)cc1)C(C)C
Molecular Formula
C68H105N11O15
CAS Number
646502-53-6

Product Categories/Family for VCMMAE biochemical

Cell Cycle/DNA Damage; Cancer

Structure of VCMMAE biochemical

VCMMAE Biochemical – Cat# MBS3607555

Product References and Citations for VCMMAE biochemical

1. Okeley, et al. Intracellular Activation of SGN-35, a Potent Anti-CD30 Antibody-Drug Conjugate. Clinicalal Cancer Research (2010), 16 (3), 888-897.

Other Notes

Small volumes of VCMMAE biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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