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CTEP (RO4956371)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607629

CTEP (RO4956371) is a novel, long-acting, orally bioavailable allosteric antagonist of mGlu5 receptor with IC50 of 2.2 nM, shows >1000-fold selectivity over other mGlu receptors. More details

$215 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CTEP, Biochemical
Full Product Name
CTEP
Product Synonym Names
RO4956371; RO-4956371; RO 4956371; CTEP
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
391.77
Suitability
DMSO: >=100mg/mL (255.25mM)
H2O: <0.1mg/mL
Target
5-HT Receptor
Receptor
mGluR5
Chemical Name
2-chloro-4-[2-[2, 5-dimethyl-1-[4-(trifluoromethoxy)phenyl]imidazol-4-yl]ethynyl]pyridine
SMILES
CC1=NC(C#CC2=CC=NC(Cl)=C2)=C(C)N1C1=CC=C(OC(F)(F)F)C=C1
Molecular Formula
C19H13ClF3N3O
CAS Number
871362-31-1

Structure of CTEP biochemical

CTEP RO4956371 Biochemical – Cat# MBS3607629

Product References and Citations for CTEP biochemical

1. Lindemann L, et al. J Pharmacol Exp Ther, 2011, 339 (2), 474-486.

Other Notes

Small volumes of CTEP biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CTEP purchase

MBS3607629 is a biochemical targeting CTEP.
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