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Motolimod (VTX-2337)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607660

Motolimod (VTX-2337) is an effective and specific Toll-like receptor (TLR) 8 agonist (EC50: 100 nM), > 50-fold selectivity over TLR7. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Motolimod, Biochemical
Full Product Name
Motolimod
Product Synonym Names
VTX-2337; VTX 2337; VTX2337; Motolimod
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
458.6
Suitability
DMSO: 50mg/mL (109.03mM)
Target
GluR
Receptor
TLR8
Chemical Name
2-amino-N, N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide
SMILES
CCCN(CCC)C(=O)C1=Cc2c(cc(cc2)c2ccc(cc2)C(=O)N2CCCC2)N=C(N)C1
Molecular Formula
C28H34N4O2
CAS Number
926927-61-9

Product Categories/Family for Motolimod biochemical

Product References and Citations for Motolimod biochemical

1.Lu H, etal.VTX-2337 is a novel TLR8 agonist that activates NK cells and augments ADCC.Clin Cancer Res. 2012 Jan 15; 18 (2):499-509.

Other Notes

Small volumes of Motolimod biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Motolimod purchase

MBS3607660 is a biochemical targeting Motolimod.
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