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GNE-617

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3607966

GNE-617, a specific NAMPT inhibitor(IC50=5 nM), shows potency in xenograft models of cancer. More details

$235 / 2 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
GNE-617, Biochemical
Full Product Name
GNE-617
Product Synonym Names
GNE-617; GNE 617; GNE617
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
427.43
Suitability
DMSO: >=42.85mg/mL (100.25mM)
Target
JNK
Receptor
NAMPT
Chemical Name
N-(4-((3, 5-difluorophenyl)sulfonyl)benzyl)imidazo[1, 2-a]pyridine-6-carboxamide
SMILES
C1=CC(=CC=C1CNC(=O)C2=CN3C=CN=C3C=C2)S(=O)(=O)C4=CC(=CC(=C4)F)F
Molecular Formula
C21H15F2N3O3S
CAS Number
1362154-70-8

Product Categories/Family for GNE-617 biochemical

MAPK/ERK Signaling; Metabolic Disease

Structure of GNE-617 biochemical

GNE-617 Biochemical – Cat# MBS3607966

Product References and Citations for GNE-617 biochemical

1.Shames DS, et al. Loss of NAPRT1 Expression by Tumor-specific Promoter Methylation Provides a Novel Predictive Biomarker for NAMPT Inhibitors. Clin Cancer Res. 2013 Dec 15; 19 (24):6912-23.

Other Notes

Small volumes of GNE-617 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for GNE-617 purchase

MBS3607966 is a biochemical targeting GNE-617.
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