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S-Ruxolitinib

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3609411

Ruxolitinib (INCB018424) is the first potent selective JAK1/2 inhibitor to enter the clinic with IC50 of 3.3 nM/2.8 nM in cell-free assays. More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
S-Ruxolitinib, Biochemical
Full Product Name
S-Ruxolitinib
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
306.37
Suitability
DMSO: 61mg/mL
Water:
Target
JAK
Receptor
JAK1; JAK2
Chemical Name
3-(4-(7H-Pyrrolo[23-d]pyrimidin-4-yl)-1H-pyrazol-1-yl)-3-cyclopentylpropanenitrile
SMILES
N#CCC(C1CCCC1)n2cc(cn2)c4ncnc3nccc34
Molecular Formula
C17H18N6
CAS Number
1160597-27-2

Product Categories/Family for S-Ruxolitinib biochemical

Myelofibrosis; Polycythaemia Vera; Angiogenesis; Cardiovascular Disease

Structure of S-Ruxolitinib biochemical

S-Ruxolitinib Biochemical – Cat# MBS3609411

Product References and Citations for S-Ruxolitinib biochemical

1.Quintas-Cardama A et al. Blood 2010 115 (15) 3109-3117.

Other Notes

Small volumes of S-Ruxolitinib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for S-Ruxolitinib purchase

MBS3609411 is a biochemical targeting S-Ruxolitinib.
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