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RS 504393

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3610108

RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 uM for human recombinant CCR2 and CCR1). More details

$265 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
RS 504393, Biochemical
Full Product Name
RS 504393
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
417.51
Suitability
DMSO: 10mg/mL (23.95mM)
Water: Insoluble
Target
CCR
Receptor
CCR2
Chemical Name
6-Methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-31-benzoxazine-44'-piperidin]-2(1H)-one
SMILES
Cc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1
Molecular Formula
C25H27N3O3
CAS Number
300816-15-3

Product Categories/Family for RS 504393 biochemical

Autophagy

Product References and Citations for RS 504393 biochemical

1.Mirzadegan T et al. Identification of the binding site for a novel class of CCR2b chemokine receptor antagonists: binding to a common chemokine receptor motif within the helical bundle. J Biol Chem. 2000 Aug 18; 275 (33):25562-71.

Other Notes

Small volumes of RS 504393 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RS 504393 purchase

MBS3610108 is a biochemical targeting RS 504393.
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