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Tyrosine kinase-IN-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3610192

Tyrosine kinase-IN-1 is a multi-targeted tyrosine kinase inhibitor(KDR Flt-1 FGFR1 and PDGFRalpha with IC50s of 4nM 20nM 4nM 2 nM respectively). More details

$220 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Tyrosine kinase-IN-1, Biochemical
Full Product Name
Tyrosine kinase-IN-1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
445.54
Suitability
DMSO: 62.5mg/mL (160.47mM)
Target
VEGFR
Receptor
KDR; Flt-1; FGFR1; PDGFRalpha; PDGFRalpha
Chemical Name
(Z)-5-((1-ethylpiperidin-4-yl)amino)-3-((3-fluorophenyl)(5-methyl-1H-imidazol-2-yl)methylene)indolin-2-one
SMILES
CCN1CCC(CC1)Nc1ccc2NC(=O)C(=C(/c3ncc(C)[nH]3)c3cccc(F)c3)c2c1
Molecular Formula
C26H28FN5O
CAS Number
705946-27-6

Product Categories/Family for Tyrosine kinase-IN-1 biochemical

Angiogenesis

Product References and Citations for Tyrosine kinase-IN-1 biochemical

1.Moon K et al. The design synthesis and biological evaluation of potent receptor tyrosine kinase inhibitors. Bioorganic & Medicinal Chemistry Letters 22 (2012) 4979-4985

Other Notes

Small volumes of Tyrosine kinase-IN-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Tyrosine kinase-IN-1 purchase

MBS3610192 is a biochemical targeting Tyrosine kinase-IN-1.
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