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TRi-1

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3610203

TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1) with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy. More details

$265 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TRi-1, Biochemical
Full Product Name
TRi-1
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
328.72
Suitability
DMSO: 62.5mg/mL (190.13mM)
Target
Other Targets
Receptor
TXNRD1
SMILES
COc1ccc(c(n1)S(=O)(=O)c1ccc(Cl)cc1)[N+]([O-])=O
Molecular Formula
C12H9ClN2O5S
CAS Number
246020-68-8

Product Categories/Family for TRi-1 biochemical

Others

Product References and Citations for TRi-1 biochemical

1.Stafford WC et al. Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapy. Sci Transl Med. 2018 Feb 14; 10 (428). pii: eaaf7444.

Other Notes

Small volumes of TRi-1 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TRi-1 purchase

MBS3610203 is a biochemical targeting TRi-1.
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