RU320521 (RU.521)

Name: RU320521 (RU.521); MyBioSource
Brand: MyBioSource
SKU: MBS3610206
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3610206

RU.521 (RU320521) is a potent dsDNA inhibitor (IC50 : 700?nM) inhibition of the dsDNA pathway by RU.521 requires the presence of cGAS. More details

$240 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RU320521, Biochemical

Full Product Name

RU320521

Product Synonym Names

RU.521

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

414.22

Suitability

DMSO: 125mg/mL (301.04mM)

Target

DNA/RNA Synthesis

Receptor

dsDNA/cGAS

SMILES

Cc1nn(-c2nc3c(Cl)c(Cl)ccc3[nH]2)c(O)c1C1OC(=O)c2ccccc12

Molecular Formula

C19H11Cl2N4O3

CAS Number

2262452-06-0

Product Categories/Family for RU320521 biochemical

Cell Cycle/DNA Damage

Product References and Citations for RU320521 biochemical

1.Vincent J et al. Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun. 2017 Sep 29; 8 (1):750.

Other Notes

Small volumes of RU320521 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for RU320521 purchase

MBS3610206 is a biochemical targeting RU320521.