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Aurora Kinase Inhibitor III

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3610347

Aurora kinase inhibitor III is a potent inhibitor of Aurora A kinase (IC50 = 42 nM).1 It is selective for Aurora A over BMX BTK IGF-1R c-Src TRKB SYK and EGFR. More details

$265 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Aurora Kinase Inhibitor III, Biochemical
Full Product Name
Aurora Kinase Inhibitor III
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
413.4
Suitability
DMSO: 50mg/mL (120.9mM)
Target
Aurora Kinase
Receptor
Aurora A
Chemical Name
N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-cyclopropanecarboxamide
SMILES
FC(F)(F)c1cccc(Nc2ccnc(Nc3cccc(NC(=O)C4CC4)c3)n2)c1
Molecular Formula
C21H18F3N5O 
CAS Number
879127-16-9

Product Categories/Family for Aurora Kinase Inhibitor III biochemical

Cell Cycle/DNA Damage

Product References and Citations for Aurora Kinase Inhibitor III biochemical

1.Zhang Q Liu Y Gao F et al. Discovery of EGFR Selective 46-Disubstituted Pyrimidines from a Combinatorial Kinase-Directed Heterocycle Library [J]. Journal of the American Chemical Society 2006 128 (7):2182-2183.

Other Notes

Small volumes of Aurora Kinase Inhibitor III biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Aurora Kinase Inhibitor III purchase

MBS3610347 is a biochemical targeting Aurora Kinase Inhibitor III.
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