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Guan-fu base A

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3611466

Guanfu base A is a potent noncompetitive CYP2D6 inhibitor (Ki: 1.20 uM in HLMs; Ki: 0.37 uM for rCYP2D6). It also inhibits HERG channel current. More details

$295 / 5 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Guan-fu base A, Biochemical
Full Product Name
Guan-fu base A
Product Synonym Names
Guanfu base A
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
429.5
Target
P450
Receptor
CYP2D6; HERG channel
SMILES
CC(=O)O[C@H]1C[C@@]2(CN3[C@@H]4[C@H]2[C@]5(C1)[C@H]3[C@]6(C([C@H]7[C@H]([C@@H]5[C@]6(C4)CC7=C)O)OC(=O)C)O)C
Molecular Formula
C24H31NO6
CAS Number
1394-48-5

Product Categories/Family for Guan-fu base A biochemical

Metabolic Enzyme/Protease

Structure of Guan-fu base A biochemical

Guan-Fu Base A Biochemical – Cat# MBS3611466

Product References and Citations for Guan-fu base A biochemical

1.Sun J et al. Guanfu base A an antiarrhythmic alkaloid of Aconitum coreanum Is a CYP2D6 inhibitor of human monkey and dog isoforms. Drug Metab Dispos. 2015 May; 43 (5):713-24.

Other Notes

Small volumes of Guan-fu base A biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Guan-fu base A purchase

MBS3611466 is a biochemical targeting Guan-fu base A.
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